There’s been a lot of hype on Twitter this year about how GLP-1 agonists [semaglutide/Ozempic, tirzepatide/Mounjaro] are “the miracle cure for obesity”.
People in the past ate more, yes, but obviously also expended more energy. A hundred years ago in Finland for example the average intake was like 3500 kcal per day, but then that was a society of agricultural manual labour.
The mice make for an interesting, big-if-true type of data point. I have another. I, as any gymrat is wont to do, have done a bit of a laboratory experiment on myself. When I’m cutting, my weight exactly tracks the loss expected by calories in calorie out model. At one point my diet for cutting included a package of Oreo cookies every day, which made no difference, calorie in calorie out.
My background is that I suffered of obesity all my life until I discovered that no actually if you just stop eating once you hit your daily calorie quota you can choose how much do you want to weight.
So in light of all this I hope you don’t mind my saying that calling calorie in calorie our obviously insane is, uh, obviosly insane. In fact to me it seems that Yudkowsky is emotionally very invested in believing that it is impossible to affect one’s bodyweight, and his judgement on the matter is clouded.
People in the past ate more, yes, but obviously also expended more energy. A hundred years ago in Finland for example the average intake was like 3500 kcal per day, but then that was a society of agricultural manual labour.
The mice make for an interesting, big-if-true type of data point. I have another. I, as any gymrat is wont to do, have done a bit of a laboratory experiment on myself. When I’m cutting, my weight exactly tracks the loss expected by calories in calorie out model. At one point my diet for cutting included a package of Oreo cookies every day, which made no difference, calorie in calorie out.
My background is that I suffered of obesity all my life until I discovered that no actually if you just stop eating once you hit your daily calorie quota you can choose how much do you want to weight.
So in light of all this I hope you don’t mind my saying that calling calorie in calorie our obviously insane is, uh, obviosly insane. In fact to me it seems that Yudkowsky is emotionally very invested in believing that it is impossible to affect one’s bodyweight, and his judgement on the matter is clouded.